Correlation between Neutrophil/Lymphocyte Ratio (NLR), lipid profile, lesion location and vascular cognitive impairment in acute ischemic stroke patients

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Correlation between Neutrophil/Lymphocyte Ratio (NLR), lipid profile, lesion location and vascular cognitive impairment in acute ischemic stroke patients

Tedjo, Raden Andi Ario - Personal Name; Prabaningtyas, Hanindia Riani - Personal Name; Hambarsari, Yetty - Personal Name; Budianto, Pepi - Personal Name; Danuaji, Rivan - Personal Name; Mirawati, Diah Kurnia - Personal Name; Suroto, Suroto - Personal Name; Benedictus, Benedictus - Personal Name; Tan, Kenneth - Personal Name; Ristinawati, Ira - Personal Name; Hafizhan, Muhammad - Personal Name; Putra, Stefanus Erdana - Personal Name; Hamidi, Baarid Luqman - Personal Name; Tejomukti, Teddy - Personal Name; Subandi, Subandi - Personal Name; Hutabarat, Ervina Arta Jayanti - Personal Name;

Background: Stroke is the leading cause of long-term disability with significant clinical and socioeconomic impact worldwide. Hyperlipidemia and inflammation play major roles in ischemic stroke. This research focuses on the correlation of three factors, namely Neutrophil-Lymphocyte Ratio (NLR), lipid profile, and lesion location, with Vascular Cognitive Impairment (VCI). These factors may serve as potential predictors for VCI.

Purpose: This research aims to study the correlation between NLR, lipid profile, and lesion location with vascular cognitive impairment. Besides, this research aims to explore those potential biomarkers as predictors of vascular cognitive impairment.

Methods: This was a cross-sectional study which included 107 patients diagnosed with ischemic stroke from February 2022 to January 2023 with a history of admission to the hospital within 72 hours. After signed an informed consent form, every patient had history taking, physical exam, lipid profile, routine blood test, Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment Indonesian Version (MoCA-Ina) on the first hospital day. Statistical tests were done with Spearman correlation method.

Results: The data distribution was not normal for INR and MoCA-INA values (p

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Series Title: Jurnal Keperawatan Padjadjaran, Vol. 12 Issue 2 August 2024
Call Number: (05) 610.5 FAK j
Publisher: Sumedang : Fakultas Keperawatan UNPAD., 2024
Collation: Hlm. 144-152
Language: English
ISBN/ISSN: 1410-4490
Classification: (05) 610.5 FAK j
Content Type: -
Media Type: -
Carrier Type: -
Edition: Vol. 12 Issue 2 August 2024
Subject(s): Stroke
Cognitive
HDL
LDL
location
NLR
Specific Detail Info: -
Statement of Responsibility: -

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Jurnal Keperawatan Padjadjaran, Vol. 12 Issue 2 August 2024

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