Aims/Introduction: The efficacy and safety of sitagliptin, a dipeptidyl peptidase (DPP)- 4 inhibitor, were compared with those of glinides in Japanese patients with type 2 diabetes. Materials and Methods: he participants were 82 patients with type 2 diabetes (glycated hemoglobin [HbA1c] ≥6.0% and
Aims/Introduction: Peroxisome proliferator activated receptor gamma (PPARG) is a nuclear hormone receptor of the ligand-dependent transcription factor involved in adipogenesis, and a molecular target of the insulin sensitizer, thiazolidinediones. The present study aimed to investigate whether the PPARG gene is associated with type 2 diabetes mellitus and its related traits within the population…
Aims/Introduction: Though there are many differences in dietary habits and in the metabolic basis between Western and Asian people, the actual dietary intake in Asian patients with diabetes has not been investigated in a nationwide setting, unlike in Western countries. We aimed to clarify dietary intake among Japanese individuals with type 2 diabetes, and identify differences in dietary intake …
Aims/Introduction: We examined secular trends in the prevalence of type 2 diabetes and prediabetes in community-dwelling Japanese subjects. Materials and Methods: A total of 2,490 subjects in 1988 and 2,852 subjects in 2002 aged 40–79 years underwent a 75-g oral glucose tolerance test, and their glucose tolerance status was defined by the 1998 World Health Organization criteria. Results: The …